Give the benefits of Creatine supplementation, should almost everyone use it?
- May 25
- 3 min read

You are taking creatine, right? 💊
At this point, I think the better question may actually be:
Why are you not taking creatine?
A brand new book, Handbook of Creatine and Creatinine In Vivo Kinetics by Mehdi Boroujerdi, Pharm.D., Ph.D., provides an excellent consolidation of what we currently know about the benefits of creatine supplementation, including the certainties, the probables and remaining unknowns.
And in clinical practice?
Most clients eventually ask me the same thing:
“Should I be taking creatine?”
For healthy adults, we very often arrive at:
Yes.
🏋️ Benefits of Creatine Supplementation
The evidence base for creatine is now enormous.
And some of the benefits are highly consistent.
📈 Increased Strength, Power & Training Capacity
This is the clearest and strongest evidence.
Creatine supplementation increases phosphocreatine stores within muscle, helping regenerate ATP, your rapid energy system for explosive exercise.
In practical terms?
That may mean:
1 or 2 extra reps
Slightly higher training intensity
Better sprint performance
Greater power output
Improved recovery between efforts
And over time?
Those small improvements compound into greater adaptation.
This is one of the reasons creatine is so consistently associated with improved strength and muscle development.
🧠 Potential Brain & Cognitive Benefits
This is where things get particularly interesting.
Emerging evidence suggests creatine may support:
Memory
Processing speed
Mood
Cognitive resilience under stress or sleep deprivation
The brain is energetically demanding.
And creatine appears to influence brain energy metabolism as well as muscle energy metabolism.
🩺 Possible Therapeutic Roles
There is also growing interest in creatine within areas including:
Parkinson’s disease
Depression
Menopause related muscle and bone loss
Age related sarcopenia
The evidence here is still evolving.
But it is increasingly difficult to think of creatine as “just a gym supplement.”
✅ Strong Safety Profile
For healthy individuals, appropriately sourced and sensibly dosed creatine has one of the strongest safety profiles in the supplement world.
That matters.
Because many supplements simply do not have this level of evidence behind them.
❌ When Creatine May Not Be Appropriate
There are situations where creatine may not be suitable.
Specific Medical Conditions
Certain medical conditions can make creatine inappropriate, including:
Chronic kidney disease (CKD)
Bipolar disorder
Other specialist clinical situations
This is why personalisation matters.
⚖️ Weight Gain Aversion
Creatine commonly increases body weight slightly through increased muscle water content and phosphocreatine storage.
For some people, this is undesirable.
I see this more commonly in women, or within sports where power-to-weight ratio matters.
🏃 Sports Where Extra Weight Can Be Unhelpful
For activities such as:
Climbing
Marathon running
Ultra-endurance events
…the extra weight may outweigh the performance benefits.
🛋️ Non-Leveraging
If someone is not engaging in exercise that develops or maintains strength, power, or muscle mass, the benefits become more speculative rather than highly predictable.
💊 Supplement Aversion
Some people simply do not enjoy taking supplements.
And that is completely reasonable.
Not everyone finds the benefits compelling enough to justify adding another daily habit.
💡 Bottom Line
Despite first discovering creatine around 30 years ago in my late teens……I still love discussing it with clients.
Because the conversation keeps evolving!
What started as a performance supplement is increasingly becoming part of broader conversations around:
Healthy ageing
Muscle preservation
Cognitive performance
Brain health
Longevity
And honestly?
For many healthy adults who exercise regularly, creatine probably offers more upside than downside.
Do you take creatine?
And if not, why not?
My clients enjoy clear, specific, actionable guidance on how to use diet, supplementation, lifestyle and functional testing to reach their personal health goals and resolve their health issues.
Why not book a free health kickstart call to find out how we would enable better health for you? 📲




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